| | | Monday, April 23rd, 2012 | | Traded 26-year-old minor league left fielder L. Gorsett, 25-year-old minor league third baseman P. Alvarez and 25-year-old starting pitcher C. Volstad to the Philadelphia Phillies, getting 20-year-old minor league third baseman M. Yi and 21-year-old minor league starting pitcher J. Knapp in return. | | Placed CL M. Corpas on the active roster. | | Activated CL M. Corpas from the disabled list. |
| Monday, April 16th, 2012 | | Placed RF J. Heyward on the 14-day disabled list. | | Purchased the contract of RF E. Beltre from Triple A Gwinnett. |
| Wednesday, March 14th, 2012 | | Signed CL B. Jenks to a 3-year contract extension worth a total of $11,750,000. |
| Monday, January 9th, 2012 | | Traded 33-year-old starting pitcher K. Lohse, 20-year-old minor league starting pitcher J. Teheran, 21-year-old minor league reliever P. Gibson and $5,000,000 in cash to the New York Mets, getting 32-year-old starting pitcher J. Santana in return. | | Placed SP J. Santana on the active roster. |
| Monday, January 2nd, 2012 | | 3B J. Crede was designated for assignment and placed on waivers. | | Placed 3B D. Wright on the active roster. | | SP G. Reynolds was designated for assignment and placed on waivers. | | Demoted CL P. Valiquette to Triple A Gwinnett. | | 3B K. Youkilis was designated for assignment and placed on waivers. |
| Saturday, December 31st, 2011 | | Signed free agent MR T. Glavine to a 1-year contract worth a total of $390,000. |
| Tuesday, December 27th, 2011 | | Signed free agent CL P. Valiquette to a 1-year contract worth a total of $390,000. |
| Saturday, December 24th, 2011 | | Traded 24-year-old minor league first baseman Y. Alonso, 30-year-old starting pitcher S. Mitre, 26-year-old minor league starting pitcher R. Jackson and 21-year-old minor league starting pitcher E. Olmos to the Chicago Cubs, getting 29-year-old third baseman D. Wright in return. |
| Saturday, December 3rd, 2011 | | RF S. Danielson received a 1-year contract through automatic renewal worth a total of $390,000. | | RF H. Bradley received a 1-year contract through automatic renewal worth a total of $390,000. | | SP J. Venters received a 1-year contract through automatic renewal worth a total of $390,000. | | SP J. Ortegano received a 1-year contract through automatic renewal worth a total of $390,000. | | SP K. Cofield received a 1-year contract through automatic renewal worth a total of $390,000. | | 2B D. Hernandez received a 1-year contract through automatic renewal worth a total of $390,000. | | RF J. Heyward received a 1-year contract through automatic renewal worth a total of $390,000. | | SP C. Volstad received a 1-year contract through automatic renewal worth a total of $390,000. | | SP E. Martin received a 1-year contract through automatic renewal worth a total of $390,000. | | CF G. Hernandez received a 1-year contract through automatic renewal worth a total of $390,000. |
| Thursday, December 1st, 2011 | | Drafted 1B A. Rizzo in the 2011 rule 5 draft (Pick 25, Round 1, 25th overall Pick). |
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